Browsing by Author "Auyeung, Bonnie"

Now showing items 1-20 of 20

    • Article  

      Alexithymia in children with and without autism spectrum disorders 

      Griffin, Cait; Lombardo, Michael V.; Auyeung, Bonnie (2016)
      Alexithymia refers to pronounced difficulty in identifying and describing one's own emotions and is associated with an externally oriented focus of thinking. Alexithymia is known to be much more common in adults with autism ...
    • Article  

      Cognition in Males and Females with Autism: Similarities and Differences 

      Lai,Meng-Chuan; Lombardo,Michael V.; Ruigrok,Amber N. V.; Chakrabarti,B.; Wheelwright,Sally J.; Auyeung, Bonnie; Allison, Carrie; Bailey, Anthony J.; Baron-Cohen,Simon; Bolton, P. F.; Bullmore,Edward T.; Carrington, S.; Catani, Marco; Craig, Michael C.; Daly,Eileen M.; Deoni,Sean C. L.; Ecker,C.; Happé,Francesca; Henty, Julian; Jezzard, Peter; Johnston,Patrick; Jones, D. K.; Madden, A.; Mullins, D.; Murphy,Clodagh M.; Murphy,Declan G. M.; Pasco, Greg; Sadek,Susan A.; Spain,D.; Stewart, R.; Suckling,John; Williams,Steven C. R.; Baron-Cohen,Simon (2012)
      The male bias in autism spectrum conditions (ASC) has led to females with ASC being under-researched. This lack of attention to females could hide variability due to sex that may explain some of the heterogeneity within ...
    • Article  

      Elevated fetal steroidogenic activity in autism 

      Baron-Cohen, Simon; Auyeung, Bonnie; Nørgaard-Pedersen, B.; Hougaard, D. M.; Abdallah, M. W.; Melgaard, L.; Cohen, A. S.; Chakrabarti, B.; Ruta, L.; Lombardo, Michael V. (2015)
      Autism affects males more than females, giving rise to the idea that the influence of steroid hormones on early fetal brain development may be one important early biological risk factor. Utilizing the Danish Historic Birth ...
    • Article  

      The EU-AIMS Longitudinal European Autism Project (LEAP): Clinical characterisation 

      Charman, T.; Loth, Eva; Tillmann, Julian; Crawley, Daisy; Wooldridge, C.; Goyard, David; Ahmad, Jumana; Auyeung, Bonnie; Ambrosino, Sara; Banaschewski, Tobias; Baron-Cohen,Simon; Baumeister, Sarah; Beckmann, Christian; Bölte, Sven; Bourgeron, Thomas; Bours, Carsten; Brammer, Michael; Brandeis, Daniel; Brogna, Claudia; De Bruijn, Y.; Chakrabarti,B.; Cornelissen, Ineke; Acqua, Flavio Dell; Dumas, G.; Durston, Sarah; Ecker,C.; Faulkner, J.; Frouin, Vincent; Garces, Pilar; Ham, Lindsay M.; Hayward, Hannah; Hipp, Joerg; Holt, R. J.; Isaksson, Johan; Johnson, Mark H.; Jones, Emily J. H.; Kundu, Prantik; Lai,Meng-Chuan; D'Ardhuy, X. L.; Lombardo,Michael V.; Lythgoe, David J.; Mandl, Rene; Mason, Luke; Meyer-Lindenberg, Andreas; Moessnang, Carolin; Mueller, Nico; O'Dwyer, Laurence; Oldehinkel, Marianne; Oranje, Bob; Pandina, Gahan J.; Persico, Antonio M.; Ruggeri, B.; Ruigrok,Amber N. V.; Sabet, Jessica; Sacco, Roberto; Caceres, Antonia San Jose; Simonoff, Emily; Toro, Roberto; Tost, Heike; Waldman, Jack; Williams,Steven C. R.; Zwiers, Marcel P.; Spooren, Will; Murphy,Declan G. M.; Buitelaar, Jan K. (2017)
      Background: The EU-AIMS Longitudinal European Autism Project (LEAP) is to date the largest multi-centre, multi-disciplinary observational study on biomarkers for autism spectrum disorder (ASD). The current paper describes ...
    • Article  

      EU-AIMS Longitudinal European Autism Project (LEAP): the autism twin cohort 

      Isaksson, Johan; Tammimies, Kristiina; Neufeld, Janina; Cauvet, Élodie; Lundin, Karl; Buitelaar, Jan K.; Loth, Eva; Murphy, Declan G. M.; Spooren, Will; Bölte, Sven; Ahmad, Jumana; Ambrosino, Sara; Auyeung, Bonnie; Banaschewski, Tobias; Baron-Cohen, Simon; Baumeister, Sarah; Beckmann, Christian; Bourgeron, Thomas; Bours, Carsten; Brammer, Michael; Brandeis, Daniel; Brogna, Claudia; de Bruijn, Yvette; Chakrabarti, Bhismadev; Charman, Tony; Crawley, Daisy; Cornelissen, Ineke; Dell’ Acqua, Flavio; Dumas, Guillaume; Durston, Sarah; Ecker, Christine; Frouin, Vincent; Garcés, Pilar; Goyard, David; Ham, Lindsay; Hayward, Hannah; Hipp, Joerg; Holt, Rosemary J.; Johnson, Mark H.; Jones, Emily J. H.; Kundu, Prantik; Lai, Meng-Chuan; D’ardhuy, Xavier Liogier; Lombardo, Michael; Lythgoe, David J.; Mandl, René; Mason, Luke; Meyer-Lindenberg, Andreas; Moessnang, Carolin; Mueller, Nico; O’Dwyer, Laurence; Oldehinkel, Marianne; Oranje, Bob; Pandina, Gahan; Persico, Antonio M.; Ruggeri, Barbara; Ruigrok, Amber; Sabet, Jessica; Sacco, Roberto; Cáceres, Antonia San José; Simonoff, Emily; Tillmann, Julian; Toro, Roberto; Tost, Heike; Waldman, Jack; Williams, Steve C. R.; Wooldridge, Caroline; Zwiers, Marcel P.; the EU-AIMS LEAP group (2018)
      EU-AIMS is the largest European research program aiming to identify stratification biomarkers and novel interventions for autism spectrum disorder (ASD). Within the program, the Longitudinal European Autism Project (LEAP) ...
    • Article  

      Fetal programming effects of testosterone on the reward system and behavioral approach tendencies in humans 

      Lombardo,Michael V.; Ashwin, Emma; Auyeung, Bonnie; Chakrabarti,B.; Lai,Meng-Chuan; Taylor, Kevin; Hackett, Gerald; Bullmore,Edward T.; Baron-Cohen,Simon (2012)
      Background: Sex differences are present in many neuropsychiatric conditions that affect emotion and approach-avoidance behavior. One potential mechanism underlying such observations is testosterone in early development. ...
    • Article  

      Fetal testosterone influences sexually dimorphic gray matter in the human brain 

      Lombardo,Michael V.; Ashwin, Emma; Auyeung, Bonnie; Chakrabarti,B.; Taylor, Kevin; Hackett, Gerald; Bullmore,Edward T.; Baron-Cohen,Simon (2012)
      In nonhuman species, testosterone is known to have permanent organizing effects early in life that predict later expression of sex differences in brain and behavior. However, in humans, it is still unknown whether such ...
    • Article  

      Improving effect size estimation and statistical power with multi-echo fMRI and its impact on understanding the neural systems supporting mentalizing 

      Lombardo,Michael V.; Auyeung, Bonnie; Holt, R. J.; Waldman, Jack; Ruigrok,Amber N. V.; Mooney, Natasha; Bullmore,Edward T.; Baron-Cohen,Simon; Kundu, Prantik (2016)
      Functional magnetic resonance imaging (fMRI) research is routinely criticized for being statistically underpowered due to characteristically small sample sizes and much larger sample sizes are being increasingly recommended. ...
    • Article  

      Intranasal oxytocin enhances intrinsic corticostriatal functional connectivity in women 

      Bethlehem, R. A. I.; Lombardo, Michael V.; Lai, Meng-Chuan; Auyeung, Bonnie; Crockford, S. K.; Deakin, J. B.; Soubramanian, S.; Sule, A.; Kundu, Prantik; Voon, Valerie; Baron-Cohen, Simon (2017)
      Oxytocin may influence various human behaviors and the connectivity across subcortical and cortical networks. Previous oxytocin studies are male biased and often constrained by task-based inferences. Here, we investigate ...
    • Article  

      Neural self-representation in autistic women and association with ‘compensatory camouflaging’: 

      Lai, Meng-Chuan; Lombardo, Michael V.; Chakrabarti, Bhismadev; Ruigrok, Amber NV; Bullmore, Edward T.; Suckling, John; Auyeung, Bonnie; Happé, Francesca; Szatmari, Peter; Baron-Cohen, Simon (2019)
      Prior work has revealed sex/gender-dependent autistic characteristics across behavioural and neural/biological domains. It remains unclear whether and how neura...
    • Article  

      Organizational effects of fetal testosterone on human corpus callosum size and asymmetry 

      Chura, Lindsay R.; Lombardo, Michael V.; Ashwin, Emma; Auyeung, Bonnie; Chakrabarti, B.; Bullmore, Edward T.; Baron-Cohen, Simon (2010)
      Previous theory and research in animals has identified the critical role that fetal testosterone (FT) plays in organizing sexually dimorphic brain development. However, to date there are no studies in humans directly testing ...
    • Article  

      Oxytocin increases eye contact during a real-time, naturalistic social interaction in males with and without autism 

      Auyeung, Bonnie; Lombardo, Michael V.; Heinrichs, M.; Chakrabarti, B.; Sule, A.; Deakin, J. B.; Bethlehem, R. A. I.; Dickens, L.; Mooney, Natasha; Sipple, J. A. N.; Thiemann, P.; Baron-Cohen, Simon (2015)
      Autism spectrum conditions (autism) affect ~1% of the population and are characterized by deficits in social communication. Oxytocin has been widely reported to affect social-communicative function and its neural underpinnings. ...
    • Article  

      Prenatal and postnatal hormone effects on the human brain and cognition 

      Auyeung, Bonnie; Lombardo, Michael V.; Baron-Cohen, Simon (2013)
      This review examines the role of hormones in the development of social and nonsocial cognition and the brain. Research findings from human studies designed to elucidate the effects of both prenatal and postnatal exposure ...
    • Article  

      The "reading the mind in the eyes" test: Complete absence of typical sex difference in 400 men and women with autism 

      Baron-Cohen, Simon; Bowen, Daniel C.; Holt, R. J.; Allison, Carrie; Auyeung, Bonnie; Lombardo, Michael V.; Smith, P.; Lai, Meng-Chuan (2015)
      The "Reading the Mind in the Eyes" test (Eyes test) is an advanced test of theory of mind. Typical sex difference has been reported (i.e., female advantage). Individuals with autism show more difficulty than do typically ...
    • Article  

      Sex Differences in the Adult Human Brain: Evidence from 5216 UK Biobank Participants 

      Ritchie, Stuart J.; Cox, Simon R.; Shen, Xueyi; Lombardo, Michael V.; Reus, Lianne M.; Alloza, Clara; Harris, Mathew A.; Alderson, Helen L.; Hunter, Stuart; Neilson, Emma; Liewald, David C. M.; Auyeung, Bonnie; Whalley, Heather C.; Lawrie, Stephen M.; Gale, Catharine R.; Bastin, Mark E.; McIntosh, Andrew M.; Deary, Ian J. (2018)
      Abstract. Sex differences in the human brain are of interest for many reasons: for example, there are sex differences in the observed prevalence of psychiatric
    • Article  

      Sex-specific impact of prenatal androgens on social brain default mode subsystems 

      Lombardo, Michael V.; Auyeung, Bonnie; Pramparo, Tiziano; Courraud, Jérémie; Holt, Rosemary J.; Waldman, Jack; Ruigrok, Amber N. V.; Mooney, Natasha; Bethlehem, Richard A. I.; Lai, Meng-Chuan; Kundu, Prantik; Bullmore, Edward T.; Mandel, Jean-Louis; Piton, Amélie; Baron-Cohen, Simon; Quartier, Angélique (2018)
      Early-onset neurodevelopmental conditions (e.g., autism) affect males more frequently than females. Androgens may play a role in this male-bias by sex-differentially impacting early prenatal brain development, particularly ...
    • Article  

      Sex/Gender Differences and Autism: Setting the Scene for Future Research 

      Lai,Meng-Chuan; Lombardo,Michael V.; Auyeung, Bonnie; Chakrabarti,B.; Baron-Cohen,Simon (2015)
      Objective The relationship between sex/gender differences and autism has attracted a variety of research ranging from clinical and neurobiological to etiological, stimulated by the male bias in autism prevalence. Findings ...
    • Article  

      Unsupervised data-driven stratification of mentalizing heterogeneity in autism 

      Lombardo,Michael V.; Lai,Meng-Chuan; Auyeung, Bonnie; Holt, R. J.; Allison, Carrie; Smith, P.; Chakrabarti,B.; Ruigrok,Amber N. V.; Suckling,John; Bullmore,Edward T.; Ecker,C.; Craig, Michael C.; Murphy,Declan G. M.; Happé,Francesca; Baron-Cohen,Simon (2016)
      Individuals affected by autism spectrum conditions (ASC) are considerably heterogeneous. Novel approaches are needed to parse this heterogeneity to enhance precision in clinical and translational research. Applying a ...
    • Article  

      Why are Autism Spectrum conditions more prevalent in Males? 

      Baron-Cohen, Simon; Lombardo, Michael V.; Auyeung, Bonnie; Ashwin, Emma; Chakrabarti, B.; Knickmeyer, Rebecca (2011)
      Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer clues to the etiology of this condition. Although the cause of this bias remains a mystery, we argue that it occurs because ASC is an ...
    • Book Chapter  

      Why is autism more common in males? 

      Baron-Cohen, Simon; Lombardo, Michael V.; Auyeung, Bonnie; Ashwin, Emma; Chakrabarti, B.; Knickmeyer, Rebecca (2014)
      Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer clues to the etiology of this condition. We argue that it occurs because ASC are an extreme manifestation of the male brain. The extreme ...